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TETRAHYDRONAPHTHALENOL.

Avoid CAS 529-33-9 / PERFUMING

TETRAHYDRONAPHTHALENOL is a chemical compound primarily used in industrial applications as a solvent and chemical intermediate. There are no identified specific benefits for skin in cosmetic formulations, and available data indicates a potential for irritation. This ingredient has not been reviewed for cosmetic safety by the Cosmetic Ingredient Review (CIR).

Science

No specific mechanism of action demonstrating skincare benefits for TETRAHYDRONAPHTHALENOL has been identified. While a related compound, 1,2,3,4-Tetrahydronaphthalene (Tetralin), is known as a bacterial fatty acid synthase antagonist, this property has not been discussed or confirmed in the context of dermatological or cosmetic applications.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Based on data for 1,2,3,4-Tetrahydronaphthalene, this compound may slowly oxidize when exposed to air, leading to the formation of naphthalene and peroxides. To maintain stability, prolonged exposure to heat, air, and light should be avoided. It is highly reactive with strong oxidants.

Conflicts

  • strong oxidizers
  • strong acids
  • strong bases

Safety

CIR Status
Not reviewed
Sensitization risk High

The Cosmetic Ingredient Review (CIR) has not conducted a safety assessment for TETRAHYDRONAPHTHALENOL or its hydroxylated isomers in cosmetic applications. Related compounds such as 1-Hydroxy-1,2,3,4-tetrahydronaphthalene and 2-Hydroxy-1,2,3,4-tetrahydronaphthalene carry GHS hazard statements for skin and serious eye irritation. Exposure to similar compounds, including 6-Hydroxy-1,2,3,4-tetrahydronaphthalene, may cause irritation and potential burns. Skin contact can lead to inflammation and possible systemic effects via absorption. The hydrocarbon 1,2,3,4-Tetrahydronaphthalene (Tetralin) is also noted for irritating skin, eyes, and mucous membranes, and is rapidly absorbed upon ingestion or inhalation.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to the lack of proven skincare benefits and a high risk of skin irritation and adverse reactions, TETRAHYDRONAPHTHALENOL is not suitable for cosmetic formulations and should be avoided.


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