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Moumoujus

TETRAHYDRO-6-NITROQUINOXALINE.

Avoid / HAIR DYEING, LIGHT STABILIZER

TETRAHYDRO-6-NITROQUINOXALINE is a chemical compound primarily utilized in medicinal chemistry and neuroscience research, particularly for modulating neurotransmitter systems. It exhibits no known cosmetic benefits for the skin and is classified as an in vitro mutagen, rendering it a prohibited ingredient for consumer cosmetic products due to significant safety concerns.

Summary

Science

Mechanism of Action

This compound's known applications are centered on medicinal chemistry, specifically in the development of neuroprotective agents and as a research tool for modulating neurotransmitter systems. No specific mechanism of action offering cosmetic benefits for skin has been identified or established.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

TETRAHYDRO-6-NITROQUINOXALINE typically appears as a pale yellow to light brown solid. A notable stability concern is its tendency to cause an orange-red discoloration upon contact with skin and to tint fur. While the free base is oil-soluble and can form aqueous suspensions (e.g., 1% with carboxymethylcellulose), its hydrochloride salt can be formulated into aqueous solutions up to 3%.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1%
Sensitization risk High

The Scientific Committee on Cosmetic Products and Non-Food Products (SCCNFP), a predecessor to the SCCS, concluded that TETRAHYDRO-6-NITROQUINOXALINE must be considered an in vitro mutagen. It is consequently listed as a prohibited substance in certain regulatory contexts and is not intended for use in consumer cosmetic products. Skin contact can lead to significant orange-red discoloration and is associated with high irritancy.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

TETRAHYDRO-6-NITROQUINOXALINE is an in vitro mutagen, causes significant skin irritation and discoloration, and is a prohibited substance for cosmetic use, making it entirely unsuitable for skincare formulations.

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