Science
Mechanism of Action
This ingredient functions by generating pressure within an aerosol system, enabling the expulsion and uniform dispersion of product contents upon valve activation.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
As a gas/propellant, tetrafluoropropene is not relevant to 'dusting' in formulations.
The Formula
Formulation
Stability
Tetrafluoropropene exhibits stability under normal environmental conditions. However, it is critical to prevent exposure to heat, sparks, and open flames due to its potential to form an explosive atmosphere in air and react violently with oxidants.
Conflicts
- air (forms explosive atmosphere)
- oxidizers
- strong bases
- alkalis
- alkaline earth metals (e.g., aluminum powder, sodium, potassium, zinc)
Safety
Safety Profile
While the FDA has concluded 'low safety concern' for tetrafluoropropene as a cosmetic propellant, this is qualified by incomplete toxicological data for many PFAS. The ingredient's classification as a PFAS raises significant concerns, including potential enhanced skin absorption, high use restrictions, moderate endocrine disruption, high persistence, and bioaccumulation. It is highlighted as a possible human carcinogen and a known human reproductive or developmental toxin by EWG Skin Deep®. Direct skin contact with the liquid form can result in frostbite.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Due to its classification as a PFAS with noted concerns regarding enhanced skin absorption, high persistence, bioaccumulation, and potential reproductive toxicity and carcinogenicity, tetrafluoropropene is not recommended for precision skincare formulations.
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