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TETRAETHYL ORTHOSILICATE.

Avoid CAS 78-10-4 / NOT REPORTED

Tetraethyl Orthosilicate (TEOS) is a silica precursor that, upon contact with moisture, hydrolyzes and condenses to form a robust, amorphous silica gel network, creating a glassy silica structure.

silica precursor silica network former

Science

TETRAETHYL ORTHOSILICATE functions by hydrolyzing its alkoxy groups to release ethanol molecules, followed by the condensation of unstable silanols (-Si-OH) into an amorphous silica gel. This process establishes a durable, glassy silica network, which can be engineered into nanoparticulate structures for applications like controlled release systems.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH 1.5 – 2.5
0 7 14

Stability

TEOS exhibits optimal stability in its hydrolyzed state within a pH range of 1.5 to 2.5, which prolongs its gelation time. Outside this narrow range, particularly between pH 5 and 6, it becomes highly unstable and rapidly gels. It slowly decomposes into silicon dioxide and ethanol upon exposure to water or atmospheric moisture.

Conflicts

  • water (reacts and decomposes)
  • strong acids (reacts exothermically)
  • oxidizing agents (e.g., nitrates, chlorine bleaches, oxidizing acids - may cause ignition)
  • alkali metals
  • hydrides

Safety

CIR Status
Not reviewed
Sensitization risk High

TETRAETHYL ORTHOSILICATE is classified as a hazardous substance, presenting as a flammable liquid and vapor. It causes serious eye irritation and may induce respiratory irritation. Direct skin contact can lead to dryness, cracking, and inflammation. Exposure of compromised skin (e.g., open cuts, abrasions) is particularly hazardous as it may facilitate entry into the bloodstream, potentially resulting in systemic injury. Ingestion carries risks of liver, kidney, and lung damage.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Given its classification as a hazardous substance with high irritation potential, flammability, and documented risks of systemic injury, TETRAETHYL ORTHOSILICATE is deemed unsuitable for cosmetic application.


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