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TETRADECANE.

Questionable CAS 629-59-4 / PERFUMING

Tetradecane functions as an emollient and solvent in skincare formulations, enhancing skin smoothness and overall product texture. Mechanistically, it exhibits potential to support skin elasticity and moisturization by influencing collagen, elastin, and hyaluronic acid production.

emollient solvent perfuming

Science

Tetradecane operates primarily as a conditioning agent, softening and smoothing the skin's surface to improve texture. Beyond its emollient properties, research indicates it may actively contribute to skin revitalization by promoting procollagen secretion, upregulating the expression of various collagen type I genes (alpha 1, alpha 2, alpha 3), and increasing elastin and hyaluronic acid levels. This multi-faceted action suggests a role in addressing visible skin wrinkles and enhancing overall skin hydration and elasticity, potentially by mitigating matrix metalloproteinase (MMP) gene expression.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ingredient demonstrates chemical inertness and robust stability at ambient temperatures, resisting oxidation. Its inclusion can also contribute to the overall antioxidant stability of a product.

Conflicts

  • strong oxidizing agents (e.g., nitric acid)

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

Tetradecane has not undergone direct review by the CIR Expert Panel, nor has the SCCS issued an opinion. While some general sources deem it safe and well-tolerated, GHS classifications and Safety Data Sheets (SDS) indicate a potential for skin and serious eye irritation. A specific study observed significant erythema and increased epidermal thickness in pig skin following 4 days of repeated exposure, warranting cautious application and further investigation into human dermal response.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

While Tetradecane shows promising mechanistic data for anti-aging and emollient properties, the absence of direct safety review by regulatory bodies and conflicting irritation data necessitate a cautious approach to its inclusion in precision skincare formulations.


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