Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

TESTICULAR EXTRACT.

Insufficient Data CAS 84540-19-2 / SKIN CONDITIONING

Testicular Extract, sourced from animal testicles, encompasses a complex mixture of biological components, notably including the enzyme hyaluronidase. While certain enzymatic actions are understood, comprehensive data regarding its specific cosmetic benefits for topical skin application is presently limited.

Summary

Science

Mechanism of Action

The primary identified enzymatic component of testicular extract, hyaluronidase, acts to hydrolyze hyaluronic acid. This breakdown activity is optimal within a pH range of 5.2 (with NaCl) to 6.0 (without NaCl). However, this mechanism is generally associated with therapeutic applications rather than established cosmetic enhancement of the skin, and broader research on testicular extracts has not focused on topical cutaneous effects.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Due to a lack of documented clinical studies specifically investigating the topical cosmetic efficacy of Testicular Extract, no effective concentration range or dusting threshold can be established. Research has not focused on its use as a general cosmetic skin enhancer.

The Formula

Formulation

Solubility
Both
Optimal pH 5.2 – 6
0 7 14

Stability

For optimal activity of bovine testicular hyaluronidase, a potential component, the pH should be maintained between 5.2 and 6.0. While general skincare formulations often target a pH range of 4 to 6 for skin compatibility, this ingredient's stability outside its enzymatic optimum for other potential components is not detailed. Historically, it has been dissolved in alcohol for subsequent dilution in aqueous or oil-based vehicles.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Testicular Extract, or its synonym Orchic Extract, has not undergone review by the Cosmetic Ingredient Review (CIR) Expert Panel for cosmetic use. There is no specific FDA status documented for this ingredient in cosmetics. Concerns regarding safety for orally consumed 'orchic extract' (derived from cow testicles) include insufficient reliable information and potential contamination from diseased animal sources, which may raise questions for topical applications as well.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

With a profound absence of documented clinical efficacy for topical skin enhancement and no safety review for cosmetic use, the utility and safety of Testicular Extract in skincare remain largely undemonstrated.

Related

Similar Ingredients

Finding similar ingredients…