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Moumoujus

TERPINYL ISOBUTYRATE.

Questionable CAS 7774-65-4 / PERFUMING

Terpinyl Isobutyrate is an aromatic ester predominantly utilized in personal care formulations for its distinct soft citrus and herbal fragrance. Its primary function is to impart scent, with no identified therapeutic benefits for the skin.

Summary

Fragrance

Science

Mechanism of Action

This ingredient operates exclusively as a fragrance component. Current research has not identified any specific mechanisms of action on the skin for therapeutic purposes, such as anti-inflammatory or antioxidant activity.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Commonly dusted

Terpinyl Isobutyrate's singular role is as a fragrance. In precision skincare, ingredients that do not offer direct functional benefits to skin health, particularly those with noted irritation potential, may be considered unnecessary or 'dusted' unless their sensory contribution is explicitly central to the product's design and outweighs any potential drawbacks.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The material demonstrates commendable stability across a variety of product types, including cosmetic creams, lotions, perfumes, and soaps. To preserve its aromatic quality, it should be stored in a cool, dry environment away from direct sunlight, with containers kept tightly sealed.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
8%
Sensitization risk Low

The Research Institute for Fragrance Materials (RIFM) has assessed Terpinyl Isobutyrate, finding it negative for both cytotoxicity and genotoxicity. Furthermore, a human maximization test utilizing a 10% concentration (6900µg/cm2 in petrolatum) indicated no skin sensitization reactions, suggesting a low sensitization risk. However, it is classified by GHS as causing skin irritation (H315) and serious eye irritation (H319) in 92.7% of cases. European regulations also label it as 'Xi - Irritant' and 'R 36/38 - Irritating to skin and eyes'. The FDA lists it as a GRAS (Generally Recognized As Safe) flavoring agent (FEMA No. 3050, GRAS No. 3). IFRA recommends usage levels up to 8.00% in fragrance concentrates.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

As an ingredient solely for fragrance, lacking therapeutic skin benefits and carrying a high potential for skin irritation, its inclusion in precision skincare formulations warrants careful consideration.

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