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TERPENES AND TERPENOIDS SINPINE.

Avoid CAS 68917-63-5 / PERFUMING

Terpenes and Terpenoids, sinpine is an oil-soluble botanical mixture primarily composed of γ-terpinene, terpinolene, limonene, and α-pinene. While its constituent limonene offers noted antimicrobial, anti-inflammatory, and antioxidant properties, the overall ingredient presents significant safety and formulation challenges.

Fragrance Antimicrobial Anti-inflammatory Antioxidant

Science

This blend of terpenes, expected to be bioavailable through dermal routes, exerts its effects primarily via limonene, a major constituent. Limonene is recognized for its antimicrobial activity, its capacity to mitigate inflammatory responses, and its antioxidant capabilities to neutralize free radicals on the skin.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The chemical is prone to rapid degradation, forming oxidation products upon exposure to air, light, or skin contact. It is imperative to incorporate antioxidants and ensure robust protection from air and light during formulation to maintain stability.

Synergies

  • Antioxidants

Conflicts

  • Oxidizing agents
  • Iodine pentafluoride and tetrafluoroethylene mixture

Safety

CIR Status
Not reviewed
Sensitization risk High

Despite an Australian evaluation indicating no hazard classification, the SCCNFP restricts use of similar Pinaceae-derived essential oils, requiring peroxide levels to be kept to the lowest possible, typically by adding antioxidants. The ingredient is registered, but scientific information is pending review, with explicit recommendations to avoid it due to its potential to cause irritation, inflammation, or dryness, particularly in high concentrations or when combined with other irritants.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Given its high irritancy risk, rapid degradation, and strong recommendations against its use, Terpenes and Terpenoids, sinpine is deemed unsuitable for precision skincare formulations.


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