Science
Mechanism of Action
This extract operates through a dual mechanism, leveraging its rich flavonoid content, including patuletin and quercetin, to provide robust antioxidant and anti-inflammatory effects. It actively scavenges free radicals, inhibits lipid peroxidation, and enhances endogenous antioxidant enzymes, safeguarding skin from environmental stressors. Concurrently, it reduces inflammation by suppressing key pro-inflammatory mediators such as cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). Beyond these core actions, Tagetes Patula Flower Extract promotes wound healing by stimulating fibroblast proliferation and exhibits potential to mitigate UV-induced damage and inhibit collagenase and elastase, enzymes implicated in skin aging.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The extract's complex composition includes both water-soluble hydrophilic components (flavonoids, polyphenols) and oil-soluble lipophilic components (essential oils, carotenoids), contributing to its dual solubility profile.
Conflicts
- Sunscreen products (due to severe phototoxicity risk)
- High concentrations in leave-on products intended for areas with potential UV exposure
Safety
Safety Profile
The Scientific Committee on Consumer Safety (SCCS) advises a maximum concentration of 0.01% for Tagetes patula extracts and essential oils in leave-on products (excluding sunscreens), contingent on the alpha terthienyl (terthiophene) content not exceeding 0.35%. Its use in sunscreen products is strictly contraindicated due to significant phototoxicity concerns. The International Fragrance Association (IFRA) similarly restricts its use to 0.010% in most leave-on categories, citing phototoxicity as a critical effect. For products applied to skin areas likely to experience sun exposure, the SCCNFP suggests not exceeding 0.05%. Isolated reports indicate potential for allergic reactions in some sensitive individuals.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite promising in vitro antioxidant and anti-inflammatory properties, the severe phototoxicity risks and stringent regulatory restrictions make Tagetes Patula Flower Extract a questionable ingredient for general cosmetic applications.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources