Science
Mechanism of Action
When polymerized into Poly[2-(tert-butylamino)ethyl methacrylate] (PTBAEMA), this compound exerts biocidal activity by displacing calcium and/or magnesium ions from bacterial outer membranes, leading to their disorganization and disruption. As a monomer, it serves as a building block for polymers and resins, where its inherent pendant amino groups are hypothesized to confer antimicrobial properties to the resulting acrylic materials.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
This ingredient's severe safety restrictions and prohibition for direct skin contact preclude its common use or 'dusting' in skincare product claims.
The Formula
Formulation
Stability
Aminomethacrylates, including T-BUTYLAMINOETHYL METHACRYLATE, are sensitive to UV light and require storage in the dark. Shorter storage durations, typically three months, are recommended compared to other methacrylate monomers. It is commonly stabilized with inhibitors such as hydroquinone or pyrogallol to prevent premature polymerization, particularly in the presence of metallic copper.
Conflicts
- Metallic copper (can induce polymerization)
Safety
Safety Profile
The CIR Expert Panel explicitly concluded that this class of methacrylate esters 'must not be in contact with the skin,' classifying it as an irritant and skin sensitizer. GHS data indicates it causes skin irritation (H315), serious eye irritation (H319), and may cause an allergic skin reaction (H317). It is also corrosive to skin and eyes and a respiratory tract irritant. Its FDA listing pertains to indirect food contact substances (food packaging), not direct cosmetic application.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Due to its classification as a severe irritant and sensitizer with a strict 0% maximum concentration for skin contact, this ingredient is entirely unsuitable and must be avoided in direct cosmetic formulations.
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