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Moumoujus

STYRENE OXIDE.

Avoid CAS 96-09-3 / NOT REPORTED

Styrene Oxide is a highly reactive epoxide primarily utilized as an industrial chemical intermediate. Due to significant safety concerns, including its classification as a probable human carcinogen and documented skin irritancy, it is deemed entirely unsuitable for precision skincare formulations.

Summary

Science

Mechanism of Action

As a reactive epoxide, Styrene Oxide is capable of interacting with the skin by disrupting its natural protective lipid barrier. This mechanism can lead to irritation and dermatitis, manifesting as dryness, redness, flaking, and cracking. In biological systems, it functions as a major metabolite of styrene, undergoing further hydrolysis to styrene glycol.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Styrene Oxide polymerizes exothermally and exhibits high sensitivity to acids, bases, air, moisture, and heat. Even trace amounts of acid in water can induce hydrolysis to racemic phenylethyleneglycol.

Conflicts

  • acids
  • bases
  • incompatible materials

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0%
Sensitization risk High

Styrene Oxide is classified by the International Agency for Research on Cancer (IARC) as Group 2A, signifying it as a probable human carcinogen with the potential to cause cancer. It is also categorized as Carcinogenicity, Category 1B by GHS. Acute exposure has been shown to cause skin and eye irritation in human subjects. The Cosmetic Ingredient Review (CIR) Expert Panel has not evaluated Styrene Oxide for cosmetic use.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Styrene Oxide is a probable human carcinogen and potent irritant with a maximum recommended concentration of 0% in cosmetics, making it entirely unsuitable and unsafe for skincare formulations.

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