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Moumoujus

STIGMASTERYL CHLORIDE.

Insufficient Data CAS 33999-16-5 / EMULSION STABILISING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Stigmasteryl Chloride is an ingredient for which specific skincare and formulation data are currently very limited. While its related compound, Stigmasterol, is a well-researched phytosterol known for its anti-inflammatory and antioxidant properties, direct evidence regarding Stigmasteryl Chloride's topical effects or safety profile in cosmetics is not readily available.

Summary

Antioxidant (based on Stigmasterol data) Anti-inflammatory (based on Stigmasterol data) Membrane dynamics regulator (based on Stigmasterol data)

Science

Mechanism of Action

Information regarding the precise mechanism of STIGMASTERYL CHLORIDE on skin is not available. However, research on its precursor, Stigmasterol, indicates significant biological activity. Stigmasterol functions as an antioxidant, actively combating oxidative stress, and exhibits anti-inflammatory effects by modulating key pathways such as iNOS and COX-2, as well as MAPK and STAT3 signaling. It also contributes to the structural integrity and physiological regulation of cell membranes.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Specific stability data for STIGMASTERYL CHLORIDE is not available. However, related compound Stigmasterol is soluble in organic solvents such as ethanol and DMSO, but sparingly soluble in water. Its high melting point may present formulation challenges, particularly when integrating into complex delivery systems.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that phytosterol ingredients, which include stigmasterol, are safe for use in cosmetics under current practices. It is crucial to note this assessment applies to stigmasterol and not specifically to STIGMASTERYL CHLORIDE. No specific SCCS opinion or FDA status for the topical use of STIGMASTERYL CHLORIDE was identified. The European Food Safety Authority (EFSA) has issued an opinion on stigmasterol-rich plant sterols as a food additive.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Due to the absence of specific research and safety data for STIGMASTERYL CHLORIDE in topical applications, its inclusion in formulations is currently not supported by robust scientific evidence.

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