Science
Mechanism of Action
Stereospermum Suaveolens Root Extract contributes to skin health by actively reducing oxidative stress through the suppression of lipid peroxidation and the enhancement of intrinsic antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH). Its anti-inflammatory efficacy is attributed to various phytochemicals, including triacontanol, flavonoids, and phenolic compounds. Furthermore, it demonstrates antimicrobial action, specifically against certain fungal pathogens.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 In rat models of Parkinson's disease, a methanolic extract demonstrated a dose-dependent increase in behavioral activity and improved muscular coordination, alongside a significant reduction in lipid peroxidation and elevated levels of antioxidant enzymes (SOD, CAT, GSH) at concentrations of 125, 250, and 500 mg/kg.
- 02 An aqueous root bark extract at 125 mg/kg significantly mitigated edema and exhibited notable anti-inflammatory effects in a carrageenan-induced paw edema rat model.
- 03 An ethanolic extract displayed strong antioxidant potential, achieving an IC50 value of 61.6±2.3 μg/mL in a DPPH free radical scavenging assay.
- 04 Antifungal activity was observed with an ethanolic extract at 500 μg/mL against human pathogenic microorganisms.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
No dedicated safety assessment for Stereospermum Suaveolens Root Extract in cosmetic applications has been conducted by regulatory bodies such as CIR, SCCS, or FDA. Therefore, specific safety parameters for topical use remain undetermined.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While preclinical and traditional uses suggest promising antioxidant, anti-inflammatory, and antimicrobial properties, comprehensive human topical efficacy and safety data are currently insufficient for definitive cosmetic application recommendations.
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