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Moumoujus

STEARIC HYDRAZIDE.

Avoid CAS 4130-54-5 / NOT REPORTED

Stearic hydrazide, a derivative of stearic acid, has been investigated for its emulsifying properties, which can help blend oil and water in cosmetic formulations. However, its use is associated with significant safety concerns, including potential for skin irritation and the formation of hazardous compounds.

Summary

Emulsifier Surfactant

Science

Mechanism of Action

The primary mechanism of stearic hydrazide involves its hydrazine group, which renders it nucleophilic, allowing it to engage in nucleophilic addition reactions with various electrophiles. In cosmetic applications, this reactivity is associated with its ability to act as an emulsifier, stabilizing oil-in-water or water-in-oil mixtures.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Generally stable under typical storage conditions, but may undergo decomposition when heated in acidic environments.

Conflicts

  • Acidic environments (accelerates decomposition upon heating)
  • Metals (can lead to complex formation)
  • Certain molecules that can induce the formation of N-nitroso compounds (NOCs)

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk High

The Cosmetic Ingredient Review (CIR) Expert Panel has determined that there is insufficient data to conclude on the safety of Stearic Hydrazide for use in cosmetic products. ECHA's GHS classification indicates it is a skin irritant, causes serious eye irritation, and may cause respiratory irritation. Additionally, hydrazides carry a risk of forming N-nitroso compounds (NOCs), which are frequently carcinogenic.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Stearic Hydrazide is not recommended for use in skincare due to a CIR rating of 'insufficient data' for safety, confirmed potential for skin and eye irritation, and the concerning risk of forming carcinogenic N-nitroso compounds.

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