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Moumoujus

STEARAMIDE.

Insufficient Data CAS 124-26-5 / OPACIFYING, SURFACTANT - FOAM BOOSTING, VISCOSITY CONTROLLING

Stearamide is a versatile lipid-derived compound primarily utilized in cosmetic formulations to enhance texture and stability. It functions as an opacifying agent, a surfactant-foam booster, and a viscosity-increasing agent, contributing to the sensory appeal and integrity of various products.

Summary

viscosity controlling foam boosting opacifying

Science

Mechanism of Action

Stearamide primarily modifies the physical characteristics of cosmetic formulations by increasing viscosity, boosting foam generation, and imparting an opaque appearance. While direct mechanistic data for Stearamide on skin is limited, related derivatives such as Stearamide MEA have been observed to exhibit anti-inflammatory and membrane-protective properties.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Clinical studies involving Stearamide derivatives provide some insights. A formulation containing 1.3% Stearamide DIBA-Stearate (further diluted to 4% of the overall formulation) demonstrated mild irritation but was found to be non-sensitizing and non-comedogenic in a repeated-insult patch test (RIPT). Separately, 5.27% Stearamide MEA did not induce sensitization during a clinical study.

Transparency

Dusting Analysis

Not commonly dusted

No data suggests this ingredient is subject to 'dusting' or exaggerated claims in the skincare industry.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Stearamide demonstrates good chemical stability, resisting degradation under typical operating temperatures. Its solubility in aqueous solutions, such as PBS at pH 7.2, is approximately 50 µg/ml, indicating primary oil solubility. Aqueous solutions are not advised for storage exceeding one day due to potential stability concerns.

Conflicts

  • Strong oxidizing agents (for Ethylene Bis Stearamide, a related compound)
  • Virtually all solvents and most polymer systems (for Ethylene Bis Stearamide, due to its dual polarity)

Safety

Safety Profile

CIR Status
Insufficient data
Max tested
3%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that the available data were insufficient to support the safety of Stearamide DIBA-Stearate, a derivative, which was reportedly used at concentrations of 1% to 3% in cosmetic products. However, Stearamide MEA (another derivative) at 5.27% was non-toxic in a 13-week dermal rat study and did not cause sensitization in a human clinical study. At a higher concentration of 17%, Stearamide MEA did not irritate rabbit skin but elicited minimal to moderate eye irritation. The FDA regulates cosmetics but does not mandate pre-market approval for most ingredients; no specific SCCS opinion was found for Stearamide.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Insufficient Data

While Stearamide offers valuable formulation benefits, comprehensive safety and efficacy data for the specific ingredient itself are currently insufficient, largely relying on studies of its derivatives.

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References

Sources