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Moumoujus

STANNOUS PYROPHOSPHATE.

Insufficient Data CAS 15578-26-4 / ANTIPLAQUE, ORAL CARE, SOOTHING

Stannous Pyrophosphate is a chemical compound acting as a source of stannous (Sn²⁺) ions and pyrophosphate (P₂O₇⁴⁻) groups, also recognized for its reducing properties. Primarily utilized in oral care for antibacterial and tartar-control benefits, its efficacy and specific mechanism in topical skincare applications are currently undocumented.

Summary

Science

Mechanism of Action

The primary mechanism involves the release of stannous (Sn²⁺) ions and pyrophosphate (P₂O₇⁴⁻) groups. In non-skin applications, stannous ions exhibit antibacterial effects and contribute to enamel strengthening, while pyrophosphate inhibits calcium phosphate crystallization. However, a distinct mechanism of action directly relevant to topical cosmetic benefits on the skin has not been thoroughly documented in the available literature.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Information regarding the dusting potential of Stannous Pyrophosphate in cosmetic formulations is not available within the provided data.

The Formula

Formulation

Solubility
Unknown
Optimal pH 4.5 – 7.5
0 7 14

Stability

Stannous Pyrophosphate exhibits limited solubility in water, although it dissolves in concentrated mineral acids and sodium pyrophosphate. It is prone to gradual oxidation from its +2 to +4 state when exposed to air or moisture, necessitating storage in sealed, well-ventilated conditions. Stability can be enhanced by incorporating antioxidants such as gentisic acid. Optimal pH for stability in reconstituted preparations ranges between 4.5 and 7.5, with some formulations optimized between 5.3 and 5.7.

Synergies

  • antioxidants

Conflicts

  • oxidizing agents
  • air
  • moisture

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Stannous Pyrophosphate is FDA approved as a diagnostic radiopharmaceutical agent for medical imaging. However, there is no specific FDA status documented for its use in topical cosmetic applications. According to PubChem's GHS classification, it 'Causes skin irritation' (H315).

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

With no documented topical skin benefits, an unreviewed CIR safety status, and a classification as a skin irritant, there is insufficient data to support its use in precision skincare.

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