Science
Mechanism of Action
Operating as a signaling peptide, SR-ESCHERICHIA COLI POLYPEPTIDE-1 activates the skin's endogenous repair mechanisms. It specifically mimics natural collagen fragments, thereby promoting the renewal of mature skin cells, reinforcing dermal structure, and contributing to a measurable reduction in visible wrinkles. Beyond its anti-aging capabilities, it provides hydration as a humectant, conditions the skin, and forms a protective film.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The stability of polypeptides produced in E. coli can be influenced by factors such as signal peptides, fusion tags, and fermentation conditions, including temperature and inducer concentration. Hydrophilic sequences, particularly those with charged residues, are known to enhance solubility and stability.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has not conducted a specific safety review for SR-ESCHERICHIA COLI POLYPEPTIDE-1, thus its status is 'not reviewed' with no established maximum concentration. While related *E. coli*-derived polypeptides are not flagged by EWG, and general protein/peptide safety is often acknowledged, this specific ingredient lacks a definitive 'safe as used' determination. The broader term 'sr-Polypeptide-1' is currently under 'unknown' status by CIR, indicating it's on a priority list for future evaluation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Further safety evaluations and specific clinical studies are needed to fully assess the optimal application and long-term effects of this polypeptide in skincare formulations.
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