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Moumoujus

SR-EGYPTIAN SCORPION OLIGOPEPTIDE-1.

Insufficient Data / SKIN CONDITIONING

SR-EGYPTIAN SCORPION OLIGOPEPTIDE-1 acts as a protective agent for the skin, fortifying it against external stressors and stimulating its innate repair processes. As a member of the broader Oligopeptide-1 family, it supports epidermal cell growth and overall skin revitalization.

Summary

Skin conditioning Skin protecting Anti-aging Regenerative Moisturizing Barrier support Anti-inflammatory Scar reduction

Science

Mechanism of Action

This oligopeptide functions as a multifaceted skin-conditioning and protecting agent. Its primary action involves promoting the proliferation and differentiation of epidermal cells, which is crucial for mitigating age-related skin thinning and enhancing cellular regeneration. It aids in comprehensive skin repair, fosters self-regeneration, stimulates new blood vessel formation, and activates rejuvenating growth factors, thereby supporting wound healing without scar formation. Additionally, it boosts keratinocyte production, reinforces the skin barrier, reduces inflammatory responses, minimizes the appearance of scars, provides sustained moisturization, and enhances the synthesis of essential extracellular matrix components like collagen, elastin, and hyaluronic acid.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 8
0 7 14

Stability

Oligopeptide-1, including its SR-EGYPTIAN SCORPION variant, is highly sensitive to pH, requiring formulations to be maintained within an optimal pH range of 5.0 to 8.0 for stability. It is also susceptible to enzymatic degradation by microorganisms, emphasizing the need for strict microbial contamination control during processing to preserve its activity.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

SR-EGYPTIAN SCORPION OLIGOPEPTIDE-1 has not been reviewed by the Cosmetic Ingredient Review (CIR) and is listed as 'Not rated' by Paula's Choice, indicating a lack of established benefits or detailed safety assessment. While the related Oligopeptide-1 (EGF) is authorized for general cosmetic use and not listed on EWG's restricted lists, its classification as a growth factor necessitates caution. Concerns exist regarding the potential for tumorigenesis if EGF signaling pathways are overexpressed or dysregulated, as EGF is implicated in various tumor cells. The long-term safety profile and substantiated preclinical bioactivity for cosmetic applications of sh-Oligopeptide-1 are subjects of ongoing scientific discussion and have been questioned.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While conceptually promising for skin regeneration and protection, SR-EGYPTIAN SCORPION OLIGOPEPTIDE-1 lacks specific clinical data, and broader concerns persist regarding the long-term safety and substantiated efficacy of related EGF peptides.

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