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SOLVENT RED 3.

Avoid CAS 6535-42-8 / HAIR DYEING

Solvent Red 3 (C.I. 12010) is a synthetic azo dye primarily employed as a colorant in cosmetic formulations. Despite its ability to impart color, its use is associated with significant safety concerns, including potential for high irritancy and regulatory restrictions in many regions.

colorant fragrance ingredient

Science

Solvent Red 3 functions as a synthetic azo dye, primarily acting on the skin to impart color to cosmetic products, skin itself, nails, or hair.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ingredient exhibits stability when exposed to 5% hydrochloric acid, showing no discernible change. It is generally stable in the presence of 5% sodium carbonate. Solvent Red 3 has a melting point of 168°C and maintains heat stability up to 120°C.

Conflicts

  • Water-based formulations (due to insolubility in water)
  • Products intended for use on or in the immediate vicinity of mucous membranes (e.g., lip and eye area, restricted in EU)
  • Cosmetic products designed for prolonged skin contact (restricted to brief contact in EU)
  • N-nitrosating agents (potential for forming N-nitrosamines, a general concern for azo dyes)

Safety

CIR Status
Not reviewed
Sensitization risk High

No specific Cosmetic Ingredient Review (CIR) report is available for Solvent Red 3 (C.I. 12010). The Scientific Committee on Consumer Safety (SCCS) has expressed broad concerns regarding azo dyes, noting that those capable of splitting into carcinogenic arylamines pose potential carcinogenic risks. For some azo dyes, including Solvent Red 3, a full risk assessment cannot be adequately performed, indicating potential consumer health risks. Consequently, European regulations impose significant restrictions on its use: it is forbidden in products applied to or near mucous membranes (such as the lip and eye areas) and is only permitted in cosmetic products with brief skin contact. Some European regulations also prohibit its use in hair dye products. It is crucial to distinguish Solvent Red 3 from FD&C Red No. 3 (Erythrosine, CI 45430), which is a distinct dye banned in the U.S. for cosmetics and topical drugs since 1990 due to animal cancer links, and whose authorization for food and ingested drugs is currently under revocation by the FDA.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Medium

Our Assessment

Avoid

Its primary function as a cosmetic colorant is outweighed by significant safety concerns, including potential carcinogenicity and high irritancy, making it unsuitable for precision skincare formulations.


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