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Moumoujus

SOLANUM MAURITIANUM EXTRACT.

Insufficient Data / HAIR CONDITIONING, SKIN CONDITIONING

Solanum Mauritianum Extract is a botanical active that demonstrates broad-spectrum antibacterial, anti-inflammatory, and antioxidant properties. This multifaceted ingredient offers potential benefits for addressing microbial imbalances, mitigating oxidative stress, and calming skin inflammation.

Summary

Antibacterial Anti-inflammatory Antioxidant Skin conditioning

Science

Mechanism of Action

The extract exerts anti-inflammatory effects by attenuating reactive oxygen species (ROS)-mediated inflammation and preventing IL-6 promoter demethylation, possibly through interaction with NOX2. Its antibacterial action is attributed to a diverse array of secondary metabolites, including alkaloids, flavonoids, saponins, tannins, steroids, and triterpenoids, which disrupt bacterial cell walls, reduce surface tension, inactivate enzymes, and obstruct protein transport. Furthermore, its antioxidant capacity is achieved through effective free radical scavenging.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrated antibacterial activity against pathogenic microbes, including Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa, at concentrations ranging from 0.0625 mg/mL to 8.0000 mg/mL. Strong antibacterial effects were specifically noted against Staphylococcus aureus at 80 mg/mL (14.54 ± 0.13 mm inhibition zone) and against Pseudomonas aeruginosa at 300 mg/mL (15.70 ± 0.09 mm inhibition zone).
  2. 02 Showed significant anti-inflammatory benefits by reducing intracellular ROS by 83% and downregulating the expression of pro-inflammatory cytokines IL-6, IL-1β, and TNF-α in PMA-activated THP-1 cells.
  3. 03 Exhibited dose-dependent DPPH radical scavenging activity, indicative of antioxidant properties, within a concentration range of 0.025-0.4 mg/mL, comparable to the synthetic antioxidant Trolox.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Formal safety assessments by bodies such as CIR, SCCS, or FDA for Solanum Mauritianum Extract in cosmetic use are currently unavailable. It is important to note that the raw Solanum mauritianum plant is considered poisonous, and handling it can cause irritation to the throat, nose, eyes, and skin due to its fine hairs, and may also induce nausea. While a cosmetic extract would likely undergo processing to mitigate such irritants, the absence of specific cosmetic safety data requires cautious evaluation.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While Solanum Mauritianum Extract shows promising in-vitro efficacy across antibacterial, anti-inflammatory, and antioxidant domains, its current 'not reviewed' safety status for cosmetic use necessitates significant caution due to known irritancy of the raw plant.

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