Science
Mechanism of Action
This extract functions via a complex profile of phytochemicals. It acts as an antioxidant by hindering oxygen-promoted reactions, which helps prevent product degradation and potentially mitigate oxidative stress on the skin. Specific components, such as solamargine, contribute to its demonstrated in vitro antifungal activity against pathogens like Trichophyton mentagrophytes and Candida albicans, and also show antibacterial action by reducing Pseudomonas aeruginosa biofilm formation.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 Solamargine (a compound within the extract) at 64 μg mL⁻¹ demonstrated in vitro antifungal activity against Trichophyton mentagrophytes and Candida albicans.
- 02 Solamargine (a compound within the extract) at 1.6 μg mL⁻¹ reduced Pseudomonas aeruginosa biofilm formation in vitro.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Saponins, present in the extract, are hydrosoluble and exhibit stability across pH variations during digestion, though they are susceptible to chemical hydrolysis by strong acids or alkalis. A specific optimal pH range for cosmetic formulation stability is not available.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not evaluated SOLANUM MAMMOSUM FRUIT EXTRACT. There are no specific safety assessments from SCCS or FDA for its use in cosmetics. The fruit is widely recognized as poisonous and toxic if ingested, due to steroidal glycoalkaloids. While historical topical uses are noted, the absence of formal safety assessments necessitates extreme caution for cosmetic application.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite exhibiting potential antioxidant and antimicrobial benefits in vitro, the lack of formal cosmetic safety assessments and the known inherent toxicity upon ingestion render this ingredient highly questionable for use in precision skincare formulations.
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