Science
Mechanism of Action
This extract's antioxidant capacity is attributed to a rich profile of phenols, tannins, flavonoids (including quercetin and kaempferol), and vitamin C, which actively neutralize free radicals. Anti-inflammatory effects are linked to compounds such as solasonine, solasodine, and various flavonoids. Furthermore, its antimicrobial action, primarily driven by alkaloids and saponins like solasonine, suggests utility in mitigating skin infections.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 An ethanolic extract of berries demonstrated 70.007 ± 0.841% DPPH inhibition at a concentration of 200 µg/mL.
- 02 A crude methanolic extract exhibited the highest zone of inhibition at 100 mg/mL against specific human pathogens.
Transparency
Dusting Analysis
There is no available data to suggest that Solanum Indicum Root Extract is commonly used as a 'dusting' ingredient for marketing purposes without substantive efficacy.
The Formula
Formulation
Safety
Safety Profile
No specific safety assessments for topical application by regulatory bodies such as CIR, SCCS, or FDA are currently available. Dermal toxicity for this extract remains 'Not determined'. General caution is advised due to concerns regarding glycoalkaloid toxicity from high oral doses of the whole plant, which can lead to gastrointestinal and neurological adverse effects. However, these concerns relate primarily to oral ingestion, and specific topical safety data is lacking.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While exhibiting promising in vitro antioxidant, anti-inflammatory, and antimicrobial properties, robust human clinical data and comprehensive topical safety assessments are currently insufficient for a definitive recommendation.
Related
Similar Ingredients
Finding similar ingredients…