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Moumoujus

SODIUM O-PHENYLPHENATE.

Avoid CAS 132-27-4 / ANTIMICROBIAL

Sodium O-Phenylphenate is an antimicrobial agent historically used as a preservative. Its application in cosmetic formulations is now severely restricted due to significant safety concerns regarding potential toxicity and irritation.

Summary

preservative antimicrobial

Science

Mechanism of Action

This ingredient functions by denaturing essential proteins and disrupting the cellular membranes of various microorganisms, effectively inhibiting their growth and survival.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Aqueous solutions of Sodium O-Phenylphenate are highly alkaline, exhibiting pH values typically ranging from 12.0 to 13.5. It rapidly dissociates into 2-phenylphenol (its free acid form) within the environmentally relevant pH range of 4-9.

Conflicts

  • Acids

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0%
Sensitization risk High

Sodium O-Phenylphenate (SOPP) has been banned for use as a preservative in cosmetic products across the EU since June 17, 2019. The Scientific Committee on Consumer Safety (SCCS) determined that SOPP exhibits enhanced skin penetration and potentially more potent toxic effects compared to o-phenylphenol, leading to its prohibition. It is categorized as a significant skin and eye irritant, with undiluted forms demonstrating corrosive potential. Furthermore, it is classified as a suspected endocrine disruptor.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to its ban in EU cosmetic products, high irritancy, suspected endocrine disruptor classification, and a 0% maximum concentration recommendation, Sodium O-Phenylphenate should be strictly avoided in skincare formulations.

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