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SODIUM MENTHYL SUCCINATE.

Questionable CAS 77341-68-5, 97439-54-8 / ASTRINGENT, DENATURANT, FLAVOURING, ORAL CARE

Sodium Menthyl Succinate is a menthol derivative primarily utilized in cosmetics to impart a cooling and refreshing sensation. It functions as a fragrance component, enhancing the sensory experience of personal care products.

Cooling Agent Fragrance Enhancer Astringent

Science

This menthol derivative is hypothesized to activate TRPM8 cold receptors on the skin, a mechanism observed with menthol that modulates calcium ion movement across cell membranes to produce a cooling effect. It may also contribute to a mild analgesic sensation by inhibiting voltage-gated Na+ channels.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Expected to be water-soluble as a sodium salt of an organic acid. While specific pH stability for Sodium Menthyl Succinate is not provided, related succinate salts demonstrate stability in a near-neutral to slightly alkaline range (pH 6.9-7.3) for at least 72 hours at 4°C or 25°C. General formulation challenges regarding aesthetics or overall stability have been noted.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Sodium Menthyl Succinate is a recognized chemical entity listed in the FDA's Global Substance Registration System (GSRS). However, it has not undergone a specific safety assessment by the CIR Expert Panel. While related mentha-derived ingredients have been deemed safe with restrictions on pulegone concentration, some sources indicate a likelihood of irritation, inflammation, or dryness. No specific SCCS opinion is available.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

While Sodium Menthyl Succinate is anticipated to provide a cooling sensation, the absence of dedicated clinical efficacy studies and a specific safety assessment by regulatory bodies, coupled with reported potential for irritation, renders its utility in precision skincare questionable.


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