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Moumoujus

SODIUM LAUROAMPHOACETATE.

Valuable CAS 66161-62-4 / CLEANSING, FOAMING, HAIR CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTING

Sodium Lauroamphoacetate is a versatile amphoteric surfactant prized for its gentle cleansing properties. It efficiently removes impurities while simultaneously enhancing foam and providing mild conditioning, making it suitable for a broad range of skincare applications.

Summary

Cleansing Surfactant Foam Boosting Hair Conditioning

Science

Mechanism of Action

Functioning as an amphoteric surfactant, Sodium Lauroamphoacetate reduces surface tension, facilitating the emulsification of oil and dirt with water for effective rinsing. It acts as both a foam booster and a conditioning agent. In acidic environments, it adopts a cationic charge, which is crucial for reducing the irritation potential of anionic co-surfactants by preventing their adsorption onto the skin. This mechanism also aids in maintaining the skin's natural pH balance.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 A Human Repeat Insult Patch Test (HRIPT) conducted on 99 subjects demonstrated that Sodium Lauroamphoacetate at 0.15% solids (equivalent to a 0.5% aqueous solution) was considered non-irritating and non-sensitizing.
  2. 02 In contrast, clinical observations revealed positive patch test reactions in some subjects when exposed to diluted hand soap containing 3.2% active Sodium Lauroamphoacetate (from a commercial product solution).
  3. 03 Further studies, including a soap chamber and epicutaneous dermal irritation assays, reported irritation at 1% and 2% active ingredient. Severe ocular irritation was also noted in in vitro assays at concentrations of 40% and 50%.

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
3.2%
Red flag below
40%

While largely considered gentle at lower concentrations, clinical data indicates that Sodium Lauroamphoacetate can cause irritation. Positive patch test reactions were observed starting at concentrations of 3.2% in certain diluted commercial products. Moreover, severe ocular irritation was noted in in vitro assays at concentrations of 40% and 50%, highlighting a significant risk at very high usage levels.

The Formula

Formulation

Solubility
Water
Optimal pH 2 – 13
0 7 14

Stability

Sodium Lauroamphoacetate exhibits exceptional stability across an extensive pH range, from 2 to 13, making it highly adaptable for various formulations. It maintains good compatibility in high electrolyte solutions and resists hard water effects. Its typical solution pH is alkaline (9-11), contributing to good microbiological stability.

Synergies

  • Reduces irritation potential of anionic co-surfactants in acidic conditions.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
30%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that Sodium Lauroamphoacetate is safe for use in cosmetics at concentrations up to 30%. A 2023 safety assessment reaffirmed these conclusions. While it does not hold a specific 'Generally Recognized As Safe' (GRAS) status from the FDA for cosmetics, its frequent use has placed it on the FDA's Voluntary Cosmetic Registration Program (VCRP) priority list.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Sodium Lauroamphoacetate is a valuable amphoteric surfactant for diverse cosmetic formulations, providing effective yet generally gentle cleansing, foam enhancement, and the unique benefit of mitigating irritation from other surfactants, provided it is used within established safe concentration limits.

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