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Moumoujus

SODIUM HYALURONATE CROSSPOLYMER.

Essential CAS 105524-32-1 / HUMECTANT, SKIN CONDITIONING

A cutting-edge, crosslinked derivative of hyaluronic acid, Sodium Hyaluronate Crosspolymer forms a resilient, three-dimensional gel network on the skin's surface. This structure creates a sustained moisture reservoir, delivering superior, long-lasting hydration and robust skin barrier support.

Summary

moisturizer/humectant skin conditioning anti-aging antioxidant

Science

Mechanism of Action

This advanced polymer establishes a stable, protective, three-dimensional gel film upon application to the skin. Functioning as an efficient moisture depot, it continuously releases bound water, significantly reducing transepidermal water loss (TEWL) and providing extended hydration. Its unique crosslinked architecture renders it highly resistant to enzymatic degradation by hyaluronidase, ensuring its prolonged presence and efficacy on the skin. Beyond its primary role as a humectant, it actively improves skin barrier function, enhances the absorption of other active ingredients, neutralizes free radicals, and visibly diminishes the appearance of fine lines and wrinkles. Its mild exfoliating action may also contribute to clearer skin by aiding in the shedding of dead skin cells.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Topical application demonstrated a 27.8% reduction in Transepidermal Water Loss (TEWL), outperforming High Molecular Weight Hyaluronic Acid (HMW-HA) which showed a 15.6% reduction.
  2. 02 In formulations combining Sodium Hyaluronate Crosspolymer with other HA types, an increase in lip volume was observed, measuring 8.5% after 3 hours and 14.2% after 30 days.
  3. 03 In vitro and in vivo studies indicated significant moisturization and a visible reduction in deep mimic wrinkles. Skin hydration improved by up to 62% within one hour when compared to high-molecular weight hyaluronic acid.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 10
0 7 14

Stability

This ingredient is sensitive to heat, with extreme pH conditions (below 4 or above 10) accelerating polymer decomposition, especially when heated. Optimal stability is maintained at pH 7 for 2 hours at 70°C or 24 hours at 50°C. At pH 5, stability is noted for 2 hours at 50°C or 24 hours at 40°C. Similarly, at pH 9, it remains stable for 2 hours at 50°C or 24 hours at 40°C.

Conflicts

  • Strong oxidation or reduction agents
  • Polymeric cationic substances (e.g., surfactants, polyquaternium-4, polyquaternium-10)
  • Multivalent metals (e.g., Zn2+, Mg2+, which can modify the integrity of the crosslinked network)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

While the CIR Expert Panel has not specifically reviewed crosslinked Hyaluronic Acid, distinguishing it from uncrosslinked Sodium Hyaluronate (deemed safe up to 7.5%), regulatory bodies such as the European Commission consider Sodium Hyaluronate Crosspolymer safe for cosmetic applications. Safety tests conducted on the powder form indicate safe use up to 1%, and it is generally regarded as non-toxic, non-irritating, with a minimal risk of allergic reactions.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Essential

Sodium Hyaluronate Crosspolymer is an essential, advanced hydrator that significantly enhances skin barrier function, provides superior long-term moisture retention, and visibly addresses signs of aging.

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