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Moumoujus

SODIUM HYALURONATE.

Valuable CAS 9067-32-7 / HUMECTANT, SKIN CONDITIONING

A derivative of hyaluronic acid, Sodium Hyaluronate is a potent humectant renowned for its ability to draw and retain significant moisture. It visibly plumps the skin, diminishes the appearance of fine lines, and promotes a supple, hydrated complexion.

Summary

skin-identical ingredient moisturizer/humectant

Science

Mechanism of Action

Sodium hyaluronate functions primarily as a humectant, actively attracting and binding water molecules from the surrounding environment and deeper dermal layers to the skin's surface. This action substantially increases skin hydration, effectively mitigating dryness and flaking, while simultaneously enhancing skin plumpness and suppleness. Its relatively low molecular weight enables deeper epidermal penetration, complementing its ability to form a surface barrier that minimizes moisture loss. Beyond hydration, it contributes to tissue repair, stimulates cellular proliferation, and supports wound healing through optimized tissue regeneration, potentially stimulating collagen synthesis and reducing inflammatory responses.

Research

Clinical Evidence

High confidence
Effective range 0.1–0.1%
Optimal

0.1%

Key findings

  1. 01 Topical application as part of a cream formulation, twice daily, significantly increased skin hydration by approximately 10% and elasticity by approximately 20%, concurrently reducing wrinkle depth by roughly 10% (hyaluronic acid salts).
  2. 02 High Molecular Weight Sodium Hyaluronate provided clinically validated hydration lasting up to 8 hours.

Transparency

Dusting Analysis

Not commonly dusted

The provided research data does not contain information regarding dusting practices for Sodium Hyaluronate in cosmetic formulations.

The Formula

Formulation

Solubility
Water
Optimal pH 5.5 – 7.5
0 7 14

Stability

Sodium Hyaluronate exhibits optimal stability within a pH range of 5.5-7.5 (or 6-8). Degradation, primarily due to hydrolysis or molecular chain breakage, occurs at pH values below 4 or above 11. It is sensitive to high temperatures, maintaining peak stability between 4°C and 25°C. To prevent degradation from light and oxidation, formulations should be stored away from direct light, and the inclusion of antioxidants may extend shelf life.

Conflicts

  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Safe as used
Max tested
7.5%
Sensitization risk Low

The Expert Panel for Cosmetic Ingredient Safety (CIR) affirmed Sodium Hyaluronate's safety in cosmetics in 2009, a conclusion reaffirmed in 2023. It is globally recognized as safe by health authorities, exhibits low toxicity, and is associated with a low incidence of severe adverse effects. The FDA has approved it for diverse medical applications, including ophthalmic solutions and dermal fillers. While the raw material isn't directly FDA-approved, products containing it must adhere to FDA regulations. It also holds 'generally recognized as safe' (GRAS) status as a food ingredient at specific serving levels.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Sodium Hyaluronate is a valuable humectant, clinically proven to enhance skin hydration, elasticity, and reduce wrinkle depth, making it a highly effective and well-tolerated ingredient across all skin types.

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