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Moumoujus

SODIUM GUAIAZULENE SULFONATE.

Valuable CAS 6223-35-4 / SURFACTANT - CLEANSING

Sodium Guaiazulene Sulfonate is a potent azulene derivative recognized for its comprehensive dermatological benefits. It effectively calms irritated skin, minimizes redness, and supports the skin's natural recovery processes. Additionally, it provides robust antioxidant defense and contributes to optimal skin hydration.

Summary

anti-inflammatory skin-soothing antioxidant wound healing skin regeneration hydration surfactant

Science

Mechanism of Action

This ingredient functions by directly targeting inflammatory pathways, significantly reducing skin redness and irritation for a more balanced complexion. It actively supports the skin's natural repair mechanisms, aiding in the healing of minor wounds and stimulating the regeneration of damaged tissue. Furthermore, it acts as a powerful antioxidant, neutralizing free radicals and protecting skin cells from environmental stressors, while also helping to maintain adequate skin moisture levels.

Research

Clinical Evidence

Medium confidence
Effective range 0.05–0.2%
Optimal

0.1%

Key findings

  1. 01 Clinical observations indicate its efficacy as an anti-irritant and anti-inflammatory agent, particularly at a recommended utilization rate of 0.1% in relevant formulations.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

Sodium Guaiazulene Sulfonate is inherently unstable as a solid at ambient temperatures, undergoing almost complete decomposition within one week when heated to 40°C. Its stability can be substantially enhanced within aqueous formulations, particularly when incorporated using granulation methods with sufficient water content (e.g., 30%). For optimal integrity, it should be introduced in the final formulation step, strictly avoiding temperatures exceeding 40°C. To maximize shelf life, storage in a refrigerator, shielded from heat and light, is recommended for up to 24 months. The inclusion of stabilizing agents, such as ActiveProtec OX (0.5%) and ActiveProtec UV (1%), is advised to prevent degradation and maintain product quality.

Synergies

  • Stabilizers (e.g., ActiveProtec OX, ActiveProtec UV) for improved stability and shelf life.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

This ingredient is approved for use in cosmetic products under European Union regulations. While generally considered safe and well-tolerated by the majority of individuals, there have been rare reports of allergic reactions or mild skin irritation, particularly in highly sensitive skin types.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Sodium Guaiazulene Sulfonate is a valuable active ingredient for precision skincare, offering clinically recognized anti-inflammatory, soothing, and antioxidant benefits across all skin types, provided its unique stability requirements are carefully managed during formulation.

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