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Moumoujus

SODIUM GLYOXYLATE.

Avoid CAS 2706-75-4 / REDUCING

Sodium Glyoxylate is an organic sodium salt derived from glyoxylic acid, primarily functioning as a reducing agent in cosmetic formulations. Its precursor, glyoxylic acid, also contributes to mild exfoliation and pH adjustment, supporting superficial skin renewal and the removal of dead skin cells. It is additionally implicated in specific metabolic pathways involving amino acids.

Summary

Reducing Agent Exfoliant pH Adjuster Skin Renewal Agent

Science

Mechanism of Action

As an organic sodium salt of glyoxylic acid, Sodium Glyoxylate functions as a reducing agent within cosmetic formulations. Its direct precursor, glyoxylic acid, provides mild exfoliating and pH-adjusting properties, facilitating the removal of dead skin cells and supporting skin renewal. Additionally, it participates in specific metabolic pathways, including amino acid metabolism.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This compound is highly hygroscopic, deliquescing rapidly and forming a syrup upon brief exposure to air. It necessitates protection from moisture to maintain stability.

Conflicts

  • oxidizing agents (nitrates, oxidizing acids, chlorine bleaches)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Sodium Glyoxylate is classified with a GHS 'Warning' pictogram, indicating it causes serious eye irritation (H319). It is also identified as an irritant to the skin, eyes, and mucous membranes. The Scientific Committee on Consumer Safety (SCCS) has not evaluated the safety of glyoxylic acid (the acid form) and has issued a call for data, citing concerns regarding potential renal toxicity, particularly when used in high-temperature applications like hair straightening. It is explicitly advised not to expose open cuts, abraded, or irritated skin to this material.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to significant safety concerns, including documented irritation and unaddressed renal toxicity risks by regulatory bodies, Sodium Glyoxylate is not recommended for precision skincare formulations.

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