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Moumoujus

SODIUM FUMARATE.

Valuable CAS 5873-57-4 / 7704-73-6 / BUFFERING

Sodium Fumarate is a water-soluble salt of fumaric acid, a compound integral to the body's citric acid cycle. In skincare, its primary function is to precisely stabilize product pH and buffer formulations, ensuring optimal efficacy and stability of other active ingredients. Beyond its foundational role, it carries potential to enhance ingredient delivery and offer subtle antioxidant or anti-inflammatory benefits, drawing from the broader actions of related fumarates.

Summary

Buffering Agent pH Adjuster Skin Penetration Enhancer (potential) Antioxidant (potential) Anti-inflammatory (potential)

Science

Mechanism of Action

Functioning primarily as a buffering agent, Sodium Fumarate precisely regulates and maintains the pH of cosmetic formulations. While direct cutaneous mechanisms are under investigation, related fumarates have demonstrated an ability to subtly enhance transdermal penetration of certain compounds by improving their distribution within the stratum corneum, without negatively impacting skin's lipid or protein structures. Furthermore, the broader fumarate class is known to interact with cellular pathways, including NRF2 and HCAR2 activation, suggesting potential antioxidant and anti-inflammatory properties through modulation of pro-inflammatory signaling.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Sodium Fumarate is an odorless, white crystalline powder that is readily soluble in water. While generally stable, formulations should avoid strong oxidizing agents, highly alkaline or acidic environments, and exposure to excessive heat, light, and moisture to maintain its integrity.

Conflicts

  • strong oxidizing agents
  • highly alkaline materials
  • highly acidic materials
  • heat
  • light
  • moisture

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed Sodium Fumarate, along with Fumaric Acid and Disodium Fumarate, safe for use in cosmetic and personal care products. The U.S. FDA also recognizes Fumaric Acid and its salts as safe food additives. No specific assessment from the SCCS was identified.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Sodium Fumarate is a valuable ingredient primarily for its essential role in precisely regulating formulation pH, with a strong safety profile and potential for subtle secondary benefits on skin.

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