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SODIUM DODOXYNOL-40 SULFATE.

Questionable CAS - / SURFACTANT - CLEANSING

Sodium Dodoxynol-40 Sulfate functions as an anionic surfactant and ethoxylated compound, adept at reducing liquid surface tension. It facilitates the mixing of oil and water, making it effective for deep cleansing and emulsification in cosmetic formulations.

Summary

Surfactant Cleansing Emulsifying Foaming

Science

Mechanism of Action

As a potent anionic surfactant, Sodium Dodoxynol-40 Sulfate effectively lowers surface tension at the oil-water interface. This action allows for thorough emulsification and dispersion of oils and dirt, enabling their removal from the skin. Its foaming properties assist in lifting impurities, ensuring comprehensive cleansing and uniform product distribution.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

A related formulation, NATEROL® SF40 (10% active matter), demonstrates transparency and stability over 3 months at temperatures ranging from 4 °C to 42.5 °C, even with up to 4% sodium chloride, without changes in aspect, viscosity, color, odor, or pH. Similar alkyl ether sulfates generally maintain stability within neutral to mildly acidic pH environments.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

While the Cosmetic Ingredient Review (CIR) has not directly assessed Sodium Dodoxynol-40 Sulfate, related compounds like 'Sodium Sulfate' are considered safe in cosmetics when properly formulated to be non-irritating, with usage up to 1% in leave-on products and as used in rinse-off applications. 'Octoxynol-40' and 'Sodium Octoxynol-9 Sulfate' have also been deemed safe for use in both rinse-off and leave-on cosmetic products. However, specific SCCS opinions or FDA statuses for this ingredient are currently unavailable.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While a powerful cleansing and emulsifying agent, Sodium Dodoxynol-40 Sulfate lacks direct safety assessment by major regulatory bodies, warranting caution for precision formulations.

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