Science
Mechanism of Action
On the skin, this ingredient operates as a conditioning agent and humectant, effectively drawing moisture into the skin and helping to retain it. It can form a delicate, protective film on the skin's surface, which minimizes transepidermal water loss, resulting in a smoother, more supple complexion and contributing to the reinforcement of the skin's natural barrier function.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 An efficacy study involving hydrolyzed keratin in a hand cream reported no adverse effects at a 3% concentration, indicating its potential for beneficial skin conditioning.
- 02 Human studies on hydrolyzed keratin demonstrated its non-irritating nature at concentrations up to 25%, establishing a high safety tolerance.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal stability for formulations containing Hydrolyzed Keratin is observed within a pH range of 5.5 to 7.5.
Safety
Safety Profile
The CIR Expert Panel concluded that keratin-derived ingredients, including Hydrolyzed Keratin, are safe under current practices of use and concentration. Hydrolyzed Keratin has been confirmed non-irritating at 100% in in vitro studies and up to 25% in human studies. No sensitization was observed in guinea pig maximization studies at up to 25% or in Human Repeat Insult Patch Tests (HRIPTs) at up to 5%. It is important to note that the 25% maximum concentration refers to Hydrolyzed Keratin generally, not specifically Sodium Cocoyl Hydrolyzed Keratin. EWG Skin Deep rates 'Cocoyl Hydrolyzed Keratin' with low concern regarding cancer, allergies & immunotoxicity, developmental & reproductive toxicity, and use restrictions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This keratin derivative is a valuable ingredient for both skin and hair formulations, offering gentle cleansing, significant conditioning, and moisture-retaining benefits with a robust safety profile.
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