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SODIUM CHITOSAN RICE BRANAMIDE HYDROXYPROPYLSULFONATE.

Insufficient Data / HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

This advanced derivative of chitosan, featuring rice bran amide and a hydroxypropylsulfonate modification, offers a multifunctional approach to skin and hair care. It acts as a conditioning, protective, and emulsifying agent, enhancing skin hydration and barrier integrity. Furthermore, it functions as a mild surfactant, aiding in cleansing and emulsion stability.

Summary

Hair Conditioning Skin Conditioning Emollient Surfactant/Cleansing Surfactant/Emulsifying Skin Protecting

Science

Mechanism of Action

As a modified chitosan derivative, this ingredient is theorized to interact with both the lipid matrix and protein components of the stratum corneum. This interaction can lead to a temporary disorganization of lipid lamellae and the formation of larger aqueous pores, potentially enhancing the permeation of other compounds. It may also increase the stratum corneum's water content and improve cell membrane fluidity. Drawing from chitosan's known properties, it is expected to provide antioxidant, antimicrobial, and anti-inflammatory benefits, contributing to moisturization, protection against bacterial colonization, and defense against oxidative stress. Its inherent surfactant capabilities enable it to reduce surface tension, facilitating the mixing of oil and water and acting as both a cleansing and emulsifying agent.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Chitosan, the base polymer, typically exhibits solubility in diluted acidic solutions (pH below its pKa of approximately 6.3) where its amino groups become protonated, promoting electrostatic repulsion and solvation. Chitosan solutions for nanoparticle applications have been successfully employed within a pH range of 3.0–7.0, demonstrating a positive zeta potential between pH 2 and 7, peaking around pH 4. While specific optimal pH for this derivative is not precisely defined, its sulfonate modification and sodium salt form are indicative of enhanced water solubility and potentially broader pH stability compared to unmodified chitosan.

Conflicts

  • Divalent cations (e.g., dicalcium phosphate dihydrate, calcium carbonate, magnesium stearate) due to the formation of coordination complexes with its amino groups.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessment for SODIUM CHITOSAN RICE BRANAMIDE HYDROXYPROPYLSULFONATE has been identified by the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or FDA in the available research.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While its multi-functional properties as a skin/hair conditioner, protective agent, and surfactant are promising, a lack of specific clinical efficacy and comprehensive safety assessments for this derivative warrants further investigation before a definitive recommendation can be made.

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