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SODIUM BUTYROYL/FORMOYL CHONDROITIN SULFATE.

Insufficient Data CAS 1000370-84-2 / SKIN CONDITIONING

A novel derivative of chondroitin sulfate, SODIUM BUTYROYL/FORMOYL CHONDROITIN SULFATE functions as a skin conditioning agent. It is anticipated to significantly enhance skin hydration and elasticity through its potent humectant properties. This ingredient shows promise for advanced formulations targeting skin regeneration and anti-aging benefits.

Skin Conditioning Humectant Anti-aging (potential) Skin Regeneration (potential)

Science

This ingredient operates primarily as a humectant, expected to attract and retain water, forming a moisturizing film on the skin's surface, similar to hyaluronic acid, thereby promoting immediate hydration and a plump feel. Based on its parent compound, chondroitin sulfate, it may also stimulate the proliferation of keratinocytes and fibroblasts, key cells in skin health, and encourage the synthesis of extracellular matrix components, including type I procollagen, which suggests potential for improving skin structure and reducing signs of aging. Its unique ionic characteristics could further facilitate controlled delivery systems for other active ingredients.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 5.5 – 7.5
0 7 14

Stability

Optimal performance, particularly concerning swelling and ingredient release from hydrogels incorporating chondroitin sulfate, is observed in neutral to slightly alkaline conditions, with pH 7.4 demonstrating maximal activity compared to more acidic environments (e.g., pH 1.2 or 4.6). The ingredient is highly water-soluble but practically insoluble in organic solvents such as ethanol, acetone, and ether.


Safety

CIR Status
Insufficient data
Sensitization risk Unknown

Specific Cosmetic Ingredient Review (CIR) or Scientific Committee on Consumer Safety (SCCS) assessments are currently unavailable for SODIUM BUTYROYL/FORMOYL CHONDROITIN SULFATE, leading to an 'insufficient data' status. While listed in some topical pain/joint creams, implying a degree of safety for its intended use, dedicated cosmetic safety assessments are lacking. Product labels for these applications advise discontinuing use if irritation or rash occurs. The parent compound, 'Chondroitin sulfate sodium', holds a GRAS (Generally Recognized As Safe) designation by the FDA for food use up to 1200 mg/person/day. A consideration for formulation involves potential allergy risk for individuals sensitive to fish protein if the chondroitin sulfate component is fish-derived.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While exhibiting promising humectant, anti-aging, and skin regenerative potentials based on its parent compound, comprehensive cosmetic safety data and clinical efficacy studies are currently insufficient to establish a definitive profile for SODIUM BUTYROYL/FORMOYL CHONDROITIN SULFATE.


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