Science
Mechanism of Action
This ingredient functions primarily through its mogroside constituents, exhibiting significant antioxidant, anti-inflammatory, and antimicrobial actions. It actively attenuates allergic skin inflammation by modulating immune responses and enhancing crucial skin barrier proteins, including SIRT1, filaggrin, and claudin-1. Furthermore, it inhibits the phosphorylation of mitogen-activated protein kinases (MAPKs), which are involved in inflammatory signaling, reduces the expression of filaggrin and chemokines in inflamed human keratinocytes, and mitigates histamine release from mast cells.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
For optimal preservation, the ingredient should be stored in a cool, dry environment, ideally below 28ºC, and shielded from direct sunlight. Refrigeration is recommended to maintain stability. When kept in its original sealed packaging under 25°C, with relative humidity below 65%, and in odor-free conditions without direct contact with walls or floors, it boasts a shelf life of 24 months.
Safety
Safety Profile
While Siraitia Grosvenorii fruit extracts have received Generally Recognized As Safe (GRAS) status from the U.S. FDA for use as a natural food sweetener, no specific safety assessment by the Cosmetic Ingredient Review (CIR) or Scientific Committee on Consumer Safety (SCCS) for topical skincare applications is currently available.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Siraitia Grosvenorii Fruit Powder offers a valuable multi-functional approach to skincare, providing antioxidant, anti-inflammatory, and barrier-supporting benefits suitable for all skin types with low irritancy and comedogenicity.
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References
Sources