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Moumoujus

SIPARUNA GUIANENSIS LEAF OIL.

Insufficient Data / FRAGRANCE

Siparuna Guianensis Leaf Oil is an essential oil recognized for its in vitro antioxidant capabilities and demonstrated antimicrobial properties. It offers potential benefits against oxidative stress and certain resistant bacterial strains in laboratory settings.

Summary

Antioxidant Antimicrobial Anti-inflammatory (traditional use)

Science

Mechanism of Action

This essential oil primarily functions by inhibiting free radicals, thereby contributing to the reduction of oxidative stress. Its antimicrobial efficacy is attributed to a high concentration of sesquiterpene hydrocarbons, which have shown synergistic and additive effects against multidrug-resistant bacterial strains. Traditional applications also suggest an anti-inflammatory action.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies demonstrate antioxidant activity, specifically inhibiting 11.1% of DPPH radicals and 15.5% of β-carotene peroxidation. These effects may vary with the oil's chemical composition.
  2. 02 In vitro research indicates synergistic and additive antimicrobial effects when combined with ampicillin against clinically resistant Staphylococcus aureus and XDR S. epidermidis strains. Synergism with gentamicin against S. epidermidis and additive effects against XDR S. epidermidis were also observed. Topical products containing the essential oil showed activity against resistant S. epidermidis.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Synergies

  • Demonstrated in vitro synergistic and additive antimicrobial effects with antibiotics (ampicillin, gentamicin) against specific multidrug-resistant bacterial strains.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Acute and subchronic toxicity research suggests low toxicity and an absence of mutagenic responses for Siparuna guianensis essential oil. However, formal safety assessments by cosmetic regulatory bodies such as CIR, SCCS, or FDA for topical application are not readily available.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While laboratory studies show promising antioxidant and antimicrobial activities, the absence of human clinical data and specific cosmetic safety assessments indicates a need for further research to establish its definitive role in skincare.

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