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Moumoujus

SILKWORM CHRYSALIS EXTRACT.

Insufficient Data CAS 91079-16-2 / SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

Silkworm Chrysalis Extract is a multifaceted ingredient derived from the Bombyx mori pupae, prized for its moisturizing, antioxidant, and potential skin-regenerating properties. It aims to enhance skin softness and flexibility by leveraging its rich lipid and protein composition.

Summary

skin conditioning moisturizing antioxidant lipid regeneration

Science

Mechanism of Action

This extract functions through several pathways: its oily component, rich in fatty acids, phytosterols, and fat-soluble vitamins (A and E), supports lipid regeneration. Antioxidant benefits are conferred by Vitamin E and carotenoids, which help protect against oxidative damage. The blend of lipids and oils works to hydrate the skin, enhancing its suppleness and smoothness, while hygroscopic proteins actively draw and retain moisture.

Research

Clinical Evidence

Medium confidence
Effective range 1–2%
Optimal

N/A

Key findings

  1. 01 Concentrations of 1% and 2% demonstrated superior moisturizing efficacy on pig skin when compared to 3% hydrolyzed collagen.
  2. 02 An in vitro study observed increased Schwann cell proliferation at a concentration of 0.25 µg/µL, indicating potential for nerve regeneration.

Transparency

Dusting Analysis

Not commonly dusted

No data available to suggest common dusting practices or specific dusting thresholds for this ingredient.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The oily components of Silkworm Chrysalis Extract may exhibit stability challenges and can develop peculiar odors. Microemulsion systems are noted as a strategy to enhance its physical and antioxidation stability.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The CIR Expert Panel issued an 'Insufficient Data Announcement' for 'Silkworm Cocoon Extract' (a related ingredient), requiring extensive data including manufacturing specifics, impurities, concentration of use, and various toxicity studies, which were not provided. Consequently, a safety conclusion remains unreached for that ingredient. While silkworm pupae oil and protein showed no cytotoxicity in cellular studies (HaCAT cells), allergic reactions (urticaria, dizziness, skin itching) have been reported in individuals consuming silkworm pupae as food. No specific SCCS opinion or FDA approval for this cosmetic ingredient has been identified.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While demonstrating promising moisturizing benefits on animal models and an intriguing mechanism for skin health, the 'insufficient data' status from the CIR Expert Panel on a closely related ingredient necessitates caution regarding its overall safety profile for widespread cosmetic application.

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