Science
Mechanism of Action
Silk proteins, including forms like hydrolyzed silk, silk amino acids, and sericin, function as sophisticated humectants, effectively attracting and binding moisture within the epidermal layers. This action significantly reduces trans-epidermal water loss (TEWL) and strengthens the skin's protective barrier against environmental stressors. Their rich amino acid profile actively stimulates the production of collagen and elastin, which enhances skin elasticity, firmness, and reduces the appearance of fine lines. Sericin, a specific silk protein, exhibits anti-inflammatory properties by inhibiting lipoxygenase, calming irritated skin, and promoting cellular regeneration and wound healing through fibroblast growth factor stimulation. Additionally, these proteins provide antioxidant benefits, safeguarding the skin from oxidative damage.
Research
Clinical Evidence
High confidence2.0-5.0%
Key findings
- 01 Increasing sericin concentration from 0.001% to 30% in a cream enhances cleansing properties and notably reduces skin irritation.
- 02 A recommended usage rate of 2-5% for hydrolyzed silk protein is established for comprehensive benefits including moisturizing, anti-aging, and skin smoothing.
- 03 Hydrolyzed silk, in a 20% aqueous solution, was determined to be a non-irritant and non-sensitizer in human skin tests.
- 04 Hydrolyzed silk, in a 6.5% aqueous solution, was confirmed to be a non-irritant in human skin tests.
Transparency
Dusting Analysis
Insufficient data available to assess dusting potential.
The Formula
Formulation
Stability
Hydrolyzed silk protein maintains stability within a pH range of 4.0 to 8.0, with degradation potentially occurring outside this range. Optimal storage is at 24°C or lower, strictly avoiding temperatures above 40°C and freezing. Protection from prolonged sunlight exposure is essential. Adequate preservation systems are critical due to the potential for microbial growth in hydrolyzed proteins. Low molecular weight (<10 kDa) hydrolyzed silk is preferred for enhanced skin penetration and efficacy.
Conflicts
- concentrated nitric acid
- concentrated sulfuric acid
- strong oxidizing agents
- gross bacterial contamination
Safety
Safety Profile
The CIR Expert Panel has comprehensively reviewed various silk derivatives, including Hydrolyzed Silk, Sericin, and Silk Powder, and affirmed their safety within current cosmetic applications and concentrations. No specific maximum concentration limit has been established by the CIR. This ingredient is generally well-tolerated across most skin types and is rarely associated with irritation or allergic reactions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Silk is a valuable multi-functional ingredient that significantly enhances skin hydration, barrier integrity, and overall resilience, making it suitable for a wide range of skin types and concerns.
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