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SILICONE QUATERNIUM-25.

Valuable CAS 385435-88-1 / HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Silicone Quaternium-25 is a specialized conditioning agent and emollient that creates a breathable, protective film on the skin. It is valued for its ability to smooth and soften the skin, enhancing the tactile experience and spreadability of cosmetic formulations.

Summary

Skin conditioning Emollient Hair conditioning Anti-static Detangling Frizz reduction Smooth silky feel Spreadability

Science

Mechanism of Action

This ingredient operates by forming a vapor-permeable, protective film on the skin's surface. Its inherently low surface tension promotes excellent spreading, contributing to overall skin maintenance. As a quaternary silicone compound, its positive charge allows it to effectively adhere to negatively charged surfaces, such as hair (imparting conditioning, anti-static, and detangling benefits), and similarly contributes to skin conditioning through enhanced adhesion and film-forming for emollient action.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No specific data regarding 'dusting' or related regulatory thresholds for Silicone Quaternium-25 were available in the research.

The Formula

Formulation

Solubility
Unknown
Optimal pH 6.59 – 7.17
0 7 14

Stability

For a related silicone quaternary microemulsion in shampoo formulations, acceptable pH values were observed within the range of 6.59 to 7.17. While general silicones are largely water-insoluble, they can be chemically modified for enhanced solubility. A comparable ingredient, Silicone Quaternium-24, is explicitly noted as water-soluble, alcohol-soluble, and hydroalcoholic soluble, suggesting potential for similar modifications in Silicone Quaternium-25.

Conflicts

  • Strong concentrated acids and bases (general silicones)
  • Small non-polar molecules like fuels and paint thinners (general silicones)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has not directly assessed Silicone Quaternium-25. In the US, most cosmetic ingredients do not require pre-market FDA approval; companies are responsible for product safety. SkinSAFE lists Silicone Quaternium-25, indicating general safe use in products. Furthermore, other related silicone quaternium compounds have been reviewed by CIR and deemed safe under established practices of use and concentration.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Silicone Quaternium-25 is a valuable conditioning agent and emollient, providing a smooth, protective feel to both skin and hair with a low potential for irritation or comedogenicity, though direct quantitative clinical efficacy data specifically for skin applications remains limited in the provided research.

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