Science
Mechanism of Action
Identified as Erythropoietin (EPO), SH-POLYPEPTIDE-72 acts as a cell signaling protein. While its primary physiological role is stimulating red blood cell production, in a cosmetic context, polypeptides generally function by binding to specific cellular receptors. This interaction can initiate events such as promoting cell proliferation, supporting tissue regeneration, and stimulating the synthesis of crucial skin proteins like collagen and elastin, thereby potentially improving skin elasticity and reducing the appearance of wrinkles. However, direct evidence for this specific polypeptide's action in skin care is not extensively detailed in current research.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
As a polypeptide with a significant molecular size and recombinant nature, SH-POLYPEPTIDE-72 is likely supplied in a lyophilized, water-soluble form. To ensure its stability, enhance skin penetration, and maintain bioactivity, its incorporation into advanced delivery systems such as liposomes or PLGA-coated nanoparticles is generally essential for topical applications.
Safety
Safety Profile
SH-POLYPEPTIDE-72 currently lacks a comprehensive safety assessment by major cosmetic review bodies, including the Cosmetic Ingredient Review (CIR), which indicates its status as 'not reviewed.' Ongoing research and the absence of specific ratings from sources like Paula's Choice highlight the need for more exhaustive safety data before widespread cosmetic application.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While identified as a growth factor, comprehensive clinical and safety data specific to SH-POLYPEPTIDE-72's topical application in skincare are currently insufficient to ascertain its precise efficacy and risk profile.
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