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Moumoujus

SH-PENTAPEPTIDE-11 SP.

Valuable / NOT REPORTED

SH-PENTAPEPTIDE-11 SP is a bio-identical Acidic Fibroblast Growth Factor (aFGF), a sophisticated cell-signaling peptide engineered to rejuvenate skin. It actively promotes cellular proliferation and reinforces the skin's structural integrity, leading to enhanced texture, resilience, and robust antioxidant defense.

Summary

cell-signaling ingredient skin regenerating wound healing antioxidant collagen synthesis booster elastin synthesis booster

Science

Mechanism of Action

Upon topical application, SH-PENTAPEPTIDE-11 SP, also identified as Acidic Fibroblast Growth Factor (aFGF), selectively binds to specific receptors on fibroblasts. This interaction initiates a cascade of cellular activities that accelerate cell proliferation and tissue regeneration. It significantly boosts the synthesis of crucial structural proteins like collagen and elastin, thereby fortifying the skin's extracellular matrix. Additionally, it exhibits powerful antioxidant properties, effectively neutralizing free radicals, mitigating cellular aging, and preventing programmed cell death and functional decline.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No specific data regarding dusting concentrations or typical inclusion percentages were found in the available research.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This peptide, like other growth factors, is susceptible to destabilization in acidic environments, which can compromise its efficacy. Formulations should avoid low pH conditions.

Conflicts

  • Alpha-hydroxy acids (AHAs)
  • Beta-hydroxy acids (BHAs)

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

While a general Cosmetics Ingredient Review (CIR) panel statement suggests peptides are safe for topical use below 10 parts per million (ppm), specific safety assessments by CIR, SCCS, or FDA for SH-PENTAPEPTIDE-11 SP are currently unavailable. Despite this, it is generally considered a safe, effective, and well-tolerated ingredient for skin application.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

SH-PENTAPEPTIDE-11 SP is a valuable, regenerating peptide with a potent mechanism for stimulating collagen and elastin, exhibiting low irritancy, though it currently lacks specific regulatory concentration guidelines.

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