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SH-OLIGOPEPTIDE-78.

Insufficient Data / HAIR CONDITIONING, SURFACTANT - CLEANSING

SH-Oligopeptide-78 is a synthetic human peptide, structurally derived from type II keratins, primarily recognized for its role in hair fiber stabilization. While detailed skin-specific mechanisms remain undefined, it belongs to a class of peptides generally understood to support cellular regeneration and skin repair processes.

Hair Conditioning Surfactant - Cleansing Antioxidant Antibacterial

Science

The primary documented mechanism for SH-Oligopeptide-78 involves the interaction of its sulfur-containing amino acids, particularly cysteine, with hair keratin. This interaction forms disulfide bonds that stabilize keratin fibers, enhancing hair integrity against thermal and chemical damage, and imparting antioxidant and antibacterial protection to the hair. Specific mechanisms of action directly targeting skin physiology have not been detailed in available research, though peptides broadly are known to signal endogenous repair pathways and contribute to skin elasticity and regeneration.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

For optimal stability, SH-Oligopeptide-78 should be stored in its original, unopened packaging in a cool, dry environment, protected from direct sunlight, heat, and moisture. Short-term storage is recommended between 2℃ and 8℃, while long-term preservation requires temperatures of -20℃±5℃.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Manufacturer data indicates minimal skin absorption, low potential for irritation or allergic reactions, and no evidence of genotoxic or carcinogenic effects. SkinSAFE further categorizes 'Oligopeptide-78' as 'Irritant Free'.


Your Skin

No Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Insufficient Data

While SH-Oligopeptide-78 demonstrates clear benefits for hair integrity and protection, there is insufficient specific data detailing its mechanism of action or efficacy directly on skin to recommend it as a primary skincare active.


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