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SH-HEPTAPEPTIDE-3.

Insufficient Data / SKIN CONDITIONING

SH-HEPTAPEPTIDE-3 is a precision-engineered synthetic peptide designed to fortify the skin's structural framework. It actively promotes collagen production and concurrently inhibits its breakdown, aiming to enhance skin firmness and elasticity.

Collagen Booster Firming Agent Elasticity Enhancer Depigmenting Agent (with L-ascorbate)

Science

This peptide exerts its action by stimulating Transforming Growth Factor-beta (TGF-β), a key signaling molecule that initiates the biosynthesis of new collagen. Simultaneously, SH-HEPTAPEPTIDE-3 inhibits matrix metalloproteases (MMPs), enzymes known for degrading collagen. This dual mechanism is intended to improve skin integrity. Furthermore, when specifically conjugated with an L-ascorbate moiety, it has been observed to inhibit melanin synthesis in vitro, suggesting a potential depigmentation effect.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Synergies

  • L-ascorbate (for potential enhanced depigmentation effect)

Safety

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments or reviews for SH-HEPTAPEPTIDE-3 from regulatory bodies such as CIR, SCCS, or FDA are currently available. Information from chemically dissimilar peptides like Acetyl Hexapeptide-8 is not considered transferable for safety evaluation due to structural and functional differences.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While SH-HEPTAPEPTIDE-3 presents a compelling biochemical mechanism for improving skin firmness, elasticity, and potential depigmentation, a lack of direct clinical efficacy and comprehensive safety review data limits a definitive recommendation.


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