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Moumoujus

SEC-BUTYL ALCOHOL.

Avoid CAS 78-92-2 / SOLVENT

Sec-butyl alcohol is an organic solvent that facilitates the dissolution and blending of diverse formulation components. While it can denature ethyl alcohol, its application to skin may lead to drying due to its lipid-dissolving properties.

Summary

solvent denaturant penetration enhancer astringent antimicrobial quick-drying agent

Science

Mechanism of Action

This compound primarily functions as a solvent, ensuring the homogeneous dispersion of ingredients within a product matrix. It can also serve as a denaturing agent for ethyl alcohol. Upon topical application, its inherent defatting capabilities can compromise the skin's natural lipid barrier, potentially inducing dryness. In broader cosmetic applications, alcohols such as sec-butyl alcohol may enhance ingredient penetration, exert astringent effects, provide antimicrobial action at higher concentrations, and contribute to rapid drying.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No data available regarding 'dusting' properties for this ingredient.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Sec-butyl alcohol is susceptible to auto-oxidation by atmospheric oxygen, leading to the formation of peroxides and peroxy compounds. Elevated temperatures accelerate this degradation. It typically exhibits a poor shelf life and should ideally be stored in a cool, dry environment and used promptly after opening. Its pKa of 17.6 indicates chemical stability against deprotonation within typical cosmetic pH ranges.

Conflicts

  • acids
  • acid chlorides
  • acid anhydrides
  • strong oxidizing agents
  • halogens
  • chlorine
  • nitrogen tetroxide
  • phosphorus trichloride
  • hypochlorous acid
  • aluminum
  • organic peroxides
  • perchloric acid
  • permonosulfuric acid
  • reducing agents
  • plastics

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Sec-butyl alcohol is characterized by moderate irritation to ocular and dermal tissues. Prolonged or repeated skin exposure may result in significant defatting and subsequent dryness. Inhalation of its vapors can irritate the respiratory tract, potentially inducing drowsiness or dizziness. Current research indicates no evidence of carcinogenicity, genotoxicity, or adverse reproductive or developmental effects.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Due to its documented moderate irritancy, defatting properties, and inherent instability, sec-butyl alcohol is not recommended for inclusion in precision skincare formulations, especially given its lack of demonstrated skin benefits.

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