Science
Mechanism of Action
This ingredient functions by dissolving other formulation components, and as a penetration enhancer, it facilitates active ingredient delivery by temporarily extracting lipids and proteins from the stratum corneum. Its astringent effect is achieved by causing a temporary contraction of skin proteins. As an antimicrobial, it denatures proteins in microbes, exhibiting strong bactericidal and fungicidal activity, yet this mechanism can also strip natural oils from the skin, leading to dryness.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 Demonstrates bacteriostatic activity against Salmonella typhimurium, Pseudomonas aeruginosa, and Klebsiella pneumoniae within 40-80% concentrations. At an 80% concentration, it exhibits bactericidal efficacy against Escherichia coli, Enterotoxigenic Escherichia coli, and Staphylococcus aureus, as observed in alcohol-based hand sanitizer formulations.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Ethanol, the foundational component, demonstrates general stability. Solutions containing 70% alcohol have shown stability for a minimum of 14 days when stored at 23-25 degrees Celsius. No specific optimal pH range for SD Alcohol 23-H's stability in cosmetic formulations has been identified.
Synergies
- Facilitates enhanced skin penetration of other active ingredients, potentially boosting their efficacy.
Conflicts
- As a penetration enhancer, it may increase skin exposure to potentially irritating or sensitizing co-ingredients.
- Its specific denaturants (acetone and Methyl Isobutyl Ketone) contribute to a higher irritation potential compared to some other alcohol denat. variants.
Safety
Safety Profile
SD Alcohol 23-H is ethyl alcohol denatured with acetone and Methyl Isobutyl Ketone (MIBK) according to regulatory standards. The Cosmetic Ingredient Review (CIR) Expert Panel has determined that denatured alcohols, including specially denatured (SD) types, are generally safe in cosmetic formulations provided the denaturants themselves are safe and systemic exposure to ethanol from dermal application is not significant. While specific maximum concentrations for SD Alcohol 23-H were not explicitly stated, the CIR panel has deemed other denatured alcohols safe for use in skincare at concentrations between 0.05% and 12%. However, this specific variant tends to be more irritating due to its denaturant composition.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While offering solvent, astringent, and antimicrobial properties useful in certain formulations, SD Alcohol 23-H's significant potential to strip natural skin oils, disrupt the skin's barrier function, and cause irritation, largely due to its specific denaturants, makes it generally unsuitable for precision skincare applications.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources