Science
Mechanism of Action
This ferment filtrate primarily operates through the action of its key component, schizophyllan—a distinctive β-(1→3)/(1→6)-glucan—and other inherent phenolic compounds. These bioactive molecules effectively neutralize free radicals, thereby mitigating oxidative stress within the skin. This mechanism contributes to its observed anti-aging (anti-wrinkle), anti-hyperpigmentation (whitening), and anti-inflammatory activities. Furthermore, schizophyllan exhibits immunomodulatory properties and potential wound-healing capabilities, acting as a biological response modifier.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Demonstrated an optimal antioxidant effect, primarily attributed to the β-glucan schizophyllan.
- 02 Showed the highest protective effect against UVB-induced radiation damage, resulting in a 23.5% increase in cell viability.
- 03 Determined as the EC50 value for antioxidant activity, specifically Ferric Reducing/Antioxidant Power (FRS).
- 04 Identified as the EC50 value for its chelating effect on ferrous ions, indicating oxidative protection.
Transparency
Dusting Analysis
No data suggests this ingredient is commonly prone to dusting in formulations.
The Formula
Formulation
Stability
This ingredient is water-soluble, with its primary active polysaccharide, schizophyllan, also exhibiting water solubility. Optimal conditions for the growth of Schizophyllum commune range from pH 3.5 to 6.5, with an ideal pH of 5.5 for mycelial growth and 5.0 for optimal protease activity, suggesting stability within this acidic to slightly acidic range.
Safety
Safety Profile
No specific safety assessments or maximum concentration limits have been published by major regulatory bodies such as the CIR, SCCS, or FDA for SCHIZOPHYLLUM COMMUNE FERMENT FILTRATE under its exact INCI name. The irritancy and comedogenicity are currently unknown based on available data.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Schizophyllum Commune Ferment Filtrate is a valuable active, demonstrating significant antioxidant and protective benefits, making it highly suitable for diverse skin types and advanced anti-aging or protective formulations.
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