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SALICYLOYLHYDROXAMIC ACID.

Avoid CAS 89-73-6 / CHELATING, SKIN CONDITIONING

Salicyloylhydroxamic acid is primarily utilized in cosmetics for its chelating and skin conditioning properties. However, its use is complicated by a significant safety profile, including classifications as a suspected carcinogen and mutagen.

chelating skin conditioning

Science

This compound acts as a chelating agent, capable of binding metal ions, which can contribute to product stability and performance. It also serves as a skin conditioning agent, though its precise mechanism for skin benefit is not extensively detailed in the context of cosmetic application. Beyond skincare, it has been noted for antibacterial effects and enzyme inhibition (urease and myeloperoxidase).


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Salicyloylhydroxamic acid is soluble in water, alcohol, and ether. It exhibits stability under normal conditions but is incompatible with strong bases and strong oxidizing agents. The compound is combustible, and its pKa is reported as 4.19 at 25°C.

Conflicts

  • strong bases
  • strong oxidizing agents

Safety

CIR Status
Not reviewed
Sensitization risk High

Salicyloylhydroxamic acid is associated with several significant hazards. It is classified as causing skin irritation (H315) and serious eye irritation (H319). It is harmful if in contact with skin or if inhaled (H312+H332) and is noted as a respiratory irritant. Furthermore, it is suspected of causing cancer (H351) and genetic defects (H341).


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to significant safety concerns, including suspected carcinogenicity, mutagenicity, and high irritancy potential, and the lack of robust clinical efficacy data for beneficial skin outcomes, this ingredient is not suitable for precision skincare formulations.


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