Science
Mechanism of Action
This fermented complex utilizes Saccharomyces cerevisiae to complex essential sea silt minerals and microelements with low molecular weight proteins, facilitating their efficient transport into skin cells. It promotes significant improvement in skin hydration, partly by activating aquaporin 3 expression, critical channels for water transport. Beyond hydration, it strengthens the skin's natural barrier, offers antioxidant defense against environmental stressors, and assists in reducing inflammation while promoting collagen production. As a prebiotic, it nurtures beneficial skin microbes, supporting a healthy microbiome, and contributes to natural odor reduction through enzymatic bio-conversion of malodorous substances.
Research
Clinical Evidence
Medium confidence10%
Key findings
- 01 In an in vitro study, concentrations of 0.25% and 0.5% increased aquaporin 3 expression by 26% and 31% respectively.
- 02 An in vivo study with 5 subjects demonstrated a vast improvement in skin hydration over 28 days when applied at 10% in an oil-in-water emulsion.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
For optimal stability, this ingredient should be incorporated during the cooling phase of a formulation. Temperatures exceeding 60°C must be avoided.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has issued an 'Insufficient Data Announcement' for the broader category of yeast-derived ingredients, requesting additional confirmatory dermal sensitization data and information on GRAS (Generally Recognized As Safe) status. While the Environmental Working Group (EWG) rates Saccharomyces/Sea Silt Ferment with 'LOW' concern for cancer, allergies, and developmental toxicity (with 'LIMITED-FAIR' data), and related ingredients like Saccharomyces Ferment Filtrate are considered safe, further comprehensive data is needed. Maximum recommended use levels for related Saccharomyces ferments are up to 5% in leave-on products and up to 10% in rinse-off products, with a 10% concentration having been studied in an in vivo hydration setting.
Your Skin
Skin Compatibility
Our Assessment
Verdict
SACCHAROMYCES/SEA SILT FERMENT presents as a valuable multi-functional ingredient, demonstrating significant hydration and barrier benefits, though further comprehensive safety and efficacy research would solidify its long-term profile.
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