Science
Mechanism of Action
The primary mechanism of this ingredient, particularly its Saccharomyces/pearl ferment lysate filtrate (PFL) component, involves targeted repair of UVB-induced skin barrier damage. It achieves this by promoting Nrf2 nuclear translocation and upregulating key antioxidant proteins, NQO1 and HO-1, thereby mitigating reactive oxygen species (ROS) accumulation. Additionally, it inhibits the c-Jun N-terminal kinase (JNK) pathway, reducing oxidative stress responses. Beyond these specific pathways, the broader Saccharomyces ferment filtrate contributes essential nutrients and antioxidants, reduces inflammation, stimulates collagen synthesis, improves skin elasticity, reinforces the skin's natural barrier, provides hydration, refines texture, and diminishes the appearance of fine lines and wrinkles.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The CIR Expert Panel has concluded that Saccharomyces Ferment Lysate Filtrate is safe for cosmetic application at concentrations up to 2%. While high-dose oral studies in mice indicated reproductive effects, these are deemed irrelevant for typical cosmetic use. The ingredient's safety is robustly supported by its data profile, GRAS (Generally Recognized As Safe) status, inherent nature, low concentrations in formulations, and a consistent absence of positive alerts in various toxicological evaluations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multifaceted ferment lysate filtrate offers significant benefits for skin barrier integrity, antioxidant defense, and overall skin health, making it a valuable asset in formulations targeting environmental protection and cellular resilience.
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References
Sources