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Moumoujus

SACCHAROMYCES/MOTHER OF PEARL FERMENT LYSATE FILTRATE.

Insufficient Data / SKIN CONDITIONING

This innovative ferment, derived from Saccharomyces yeast interacting with Mother of Pearl, is engineered to actively repair and fortify the skin barrier. It demonstrates potent antioxidant and anti-inflammatory capabilities, enhancing skin resilience against environmental stressors such as UVB radiation.

Summary

Skin Conditioning Antioxidant Barrier Repair Anti-inflammatory Moisturizing Skin Regeneration Collagen Boosting Elasticity Enhancing Sebum Regulation Skin Tone Improvement

Science

Mechanism of Action

Saccharomyces/Mother Of Pearl Ferment Lysate Filtrate (PFL) intervenes at a cellular level to counteract UVB-induced skin damage. Its primary action involves stimulating the Nrf2 pathway, leading to an upregulation of crucial antioxidant proteins like NQO1 and HO-1, which effectively reduces reactive oxygen species (ROS) accumulation. Concurrently, PFL inhibits the c-Jun N-terminal kinase (JNK) pathway, thereby mitigating oxidative stress responses. This dual action restores proteins vital for epidermal differentiation, tight junction integrity, and optimal moisture retention, while also reducing inflammatory mediators. Broader research on related Saccharomyces ferments suggests a rich nutrient profile, including polysaccharides, peptides, vitamins, minerals, and amino acids, which collectively contribute to improved skin elasticity, radiance, moisture, regulated sebum production, enhanced skin tone, and support for collagen and soluble elastin synthesis.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has issued an 'Insufficient Data Announcement' for a group of 56 yeast-derived ingredients, including 'Saccharomyces Ferment Lysate Filtrate', requesting specific confirmatory dermal sensitization data and information regarding food use/GRAS status. While some dermal, ocular, phototoxicity data, and Human Repeat Insult Patch Tests (HRIPT) have been received for the broader 'Saccharomyces Ferment Lysate Filtrate', a definitive CIR safety conclusion for the specific 'Saccharomyces/Mother Of Pearl Ferment Lysate Filtrate' remains pending due to the broader group's status. For the related 'Saccharomyces Ferment Filtrate', it is generally considered safe for cosmetic use, with no reported side effects, typically at concentrations of 0.1%-5% in leave-on and up to 10% in rinse-off products.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

This ingredient presents compelling preclinical evidence for repairing and protecting the skin barrier against UVB damage, offering broad skin-conditioning benefits; however, a definitive safety conclusion from the CIR for this specific ferment remains pending.

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